GWES is a free web server for high-throughput genome-wide epistasis (gene-gene interaction) studies. It provides the first integrative solution for detecting genome-wide epistasis patterns, mapping the detected loci to known genes based on user defined mapping windows, and carrying out functional enrichment analysis for the significant genetic markers. The tool employs high-throughput epistasis analysis methods and takes advantages of a powerful computer cluster enabling efficient parallel job execution. It is also coupled with various visualizations that help the user in the result interpretation. GWES has already been successfully used for various epistasis studies.

Please see the tutorial for short usage examples and user guide for more detailed descriptions.

Start GWES Webserver.

GWES has been developed as a collaboration between MRC Human Genetics Unit and the Finnish Microarray and Sequencing Centre.


Contact: attila.gyenesei at